Metallothioneins, Unconventional Proteins from Unconventional Animals: A Long Journey from Nematodes to Mammals

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Metallothioneins, Unconventional Proteins from Unconventional Animals: A Long Journey from Nematodes to Mammals †

Metallothioneins (MTs) are ubiquitous low molecular weight cysteine-rich proteins characterized by high affinity for d10 electron configuration metals, including essential (Zn and Cu) and non-essential (Cd and Hg) trace elements. The biological role of these ancient and well-conserved multifunctional proteins has been debated since MTs were first discovered in 1957. Their main hypothesized func...

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ژورنال

عنوان ژورنال: Biomolecules

سال: 2014

ISSN: 2218-273X

DOI: 10.3390/biom4020435